Selection of Grubbs Catalysts
M100 Series
Grubbs Catalyst® 1st Generation
The Original - Terminal olefin selectivity
|
LIGAND L |
TRADE NAME | CHEMICAL FORMULA | CAS NUMBER |
| PCy3 | Grubbs Catalyst® M101 Ultrapure | Ru(PCy3)2(Ind)Cl2 | 250220-36-1 |
| PCy3 | Grubbs Catalyst® M102 | Ru(PCy3)2(benzylidene)Cl2 | 172222-30-9 |
| PCy3 | Grubbs Catalyst® M103 | Ru(PCy3)2(butenylidene)Cl2 | 194659-03-5 |
| PCy3 | Grubbs Catalyst® M104 | Ru(PCy3)2(2-thienylmethylene)Cl2 | 1190427-44-1 |
| iBu-phobane | Grubbs Catalyst® M110 | Ru(iBu-phobane)2(Ind)Cl2 | 894423-99-5 |
M200 Series
Grubbs Catalyst® 2nd Generation
Highly active - Versatile
|
NHC |
LIGAND L1 |
LIGAND L2 |
TRADE NAME | CHEMICAL FORMULA | CAS NUMBER |
| SIMes | PPh3 | Cl | Grubbs Catalyst® M200 | (SIMes)Ru(PPh3)(Ind)Cl2 | 340810-50-6 |
| SIPr | PPh3 | Cl | Grubbs Catalyst® M201 | (SIPr)Ru(PPh3)(Ind)Cl2 | 1307233-23-3 |
| SIMes | PCy3 | CI | Grubbs Catalyst® M202 | (SIMes)Ru(PCy3)(Ind)Cl2 | 536724-67-1 |
| IMes | PCy3 | Cl | Grubbs Catalyst® M203 | (IMes)Ru(PCy3)(Ind)Cl2 | 254972-49-1 |
| SIMes | PCy3 | - | Grubbs Catalyst® M204 | (SIMes)Ru(PCy3)(benzylidene)Cl2 | 246047-72-3 |
| SIPr | PCy3 | - | Grubbs Catalyst® M206 | (SIPr)Ru(PCy3)(benzylidene)Cl2 | 373640-75-6 |
| SIMes | PCy3 | - | Grubbs Catalyst® M207 | (SIMes)Ru(PCy3)(butenylidene)Cl2 | 253688-91-4 |
| IMes | Cl | PCy3 | Grubbs Catalyst® M208 | [(Me)2-IMes]Ru(PCy3)(2-thienylmethylene)Cl2 | 1190427-50-9 |
| IMes | Cl | PCy3 | Grubbs Catalyst® M209 | (IMes)Ru(PCy3)(2-thienylmethylene)Cl2 | 1190427-49-6 |
| SIMes | Cl | P(OiPr)3 | Grubbs Catalyst® M220 | (SIMes)Ru(P(OiPr)3)(Ind)Cl2 | 1255536-61-8 |
M300 Series
Grubbs Catalyst® Fast-initiating
Labile Ligands - Bench-stable
|
NHC |
LIGAND L1 |
LIGAND L2 |
TRADE NAME | CHEMICAL FORMULA | CAS NUMBER |
| SIMes | py | - | Grubbs Catalyst® M310 | (SIMes)Ru(py)(Ind)Cl2 | 1031262-76-6 |
M700 Series
Grubbs Catalyst® Hoveyda-type
Highly stable - Active at low temperature
|
NHC |
R |
LIGAND L |
TRADE NAME | CAS NUMBER |
| - | - | PCy3 | Hoveyda Grubbs Catalyst® M700 | 203714-71-0 |
| SIMes | NH(CO)CF3 | - | Hoveyda Grubbs Catalyst® M710 | 1025728-56-6 |
| SIPr | NH(CO)CF3 | - | Hoveyda Grubbs Catalyst® M711 | 1212008-99-5 |
| SIMes | H | - | Hoveyda Grubbs Catalyst® M720 | 301224-40-8 |
| SI(o-Tol) | H | - | Hoveyda Grubbs Catalyst® M721 | 927429-61-6 |
| SIPr | H | - | Hoveyda Grubbs Catalyst® M722 | 635679-24-2 |
| SIMes | NH(CO)OiBu | - | Hoveyda Grubbs Catalyst® M730 | 1025728-57-7 |
| SIPr | NH(CO)OiBu | - | Hoveyda Grubbs Catalyst® M731 | 1212009-05-6 |
M800 Series
Grubbs Catalyst® Latent
Bis-NHC coordinated - Stable at high temperature - Thermally activated
|
NHC |
TRADE NAME | CHEMICAL FORMULA | CAS NUMBER |
| SIMes | Grubbs Catalyst® M800 | (SIMes)2Ru(Ind)Cl2 | 1383684-54-5 |
M1000 Series
Hoveyda Grubbs Catalyst® CAAC-Coordinated
Unprecedented TON - Ethylene resistant - Terminal olefin selectivity
| TRADE NAME | CHEMICAL FORMULA | CAS NUMBER |
| Hoveyda Grubbs Catalyst® M1001 | C32H39Cl2NORu | 1632041-02-1 |
| Hoveyda Grubbs Catalyst® M1002 | C35H45Cl2NORu | 1206687-43-5 |
M2000 Series
Hoveyda Grubbs Catalyst® Z-Selective
Terminal olefin selectivity - High turnover number
| TRADE NAME | CAS NUMBER |
| Hoveyda Grubbs Catalyst® M2001 | 1352916-84-7 |
