Advanced catalyst technologies for efficient cross-coupling reactions

Cross-coupling reactions are among the most efficient and synthetically versatile bond-forming methodologies, enabling the preparation of a broad range of molecules from pharmaceuticals and agrochemicals to OLED materials.

Despite their versatility, finding the optimal catalyst for a specific application remains a significant challenge for process chemists, often requiring rounds of screening. Umicore supports this by offering an extensive and expertly curated portfolio of cross-coupling catalysts composed of Palladium-phosphine complexes, Pd-NHCs, high performance and partially patent protected catalysts, in addition to recently developed Nickel complexes.

Developed for stability and ease of use, these precatalysts are designed to overcome the common hurdles of in situ catalyst formation, ensuring process chemists can identify a robust and scalable solution for even the most challenging reactions.