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[Au(en)2]Cl3

[Au(en)2]Cl3

Bis(ethylenediamine)gold(III) trichloride

CAS Number: 15278-22-5

Chemical properties

Chemical formula

C4H16N4Cl3Au

Empirical formula

[Au(en)2]Cl3

Molecular weight

423.52

Metal

Au

Theoretical metal content

47

Physical state

powder

Color

beige

Metal purity

99.9

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Applications & references

Description

Aerobic oxidative C-C-coupling of cyclic amines with nitromethane.

Reference: Angew. Chem. Int. Ed. 2012, 51, 1252 (DOI: 10.1002/anie.201107605)

 

Potential antitumor agent.

Gold(III) complexes normally show promising cytotoxic and antitumor properties. Due to the coordination of multidentate ligands, e.g. ethylenediamine, the stability of the gold(III) complexes are enhanced. Thus, these complexes exhibit sufficient stability under physiological conditions. Their cytotoxic properties could be observed on the representative human ovarian tumor cell line A2780, either resistant or sensitive to cisplatinum.

Reference: J. Med. Chem. 2000, 43, 3541 (DOI: DOI: 10.1021/jm990492u)