Expanding Asymmetric Catalysis: Ligand and Screening Capabilities at Umicore PMC 

Strengthening our capabilities in catalysis and ligand chemistry

As part of this expansion, Umicore PMC incorporates key elements that enhance both technical capabilities and development efficiency:

• Ligand libraries, including a wide range of research ligands
• High throughput screening workflows, methods, and tools
• Analytical and automation equipment
• Extensive know-how in ligand development and application 

By bringing these elements together, PMC further strengthens its role as a global partner for catalysis and reaction optimization.

What this means for customers 

This is more than a portfolio expansion. It changes how customers can approach process development:

• Accelerated route development, supported by integrated screening and ligand selection
• Simplified sourcing, with ligands, metal precursors, and catalysts available from one supplier
• Scalable solutions, from early-stage development to industrial production
• Combined expertise across screening, ligand chemistry, and catalysis

The result is a more streamlined and efficient development process with fewer interfaces and greater consistency.

Broadening the ligand portfolio

Umicore PMC is progressively implementing key ligand families that complement its existing offering, including:

• Mandyphos
• Taniaphos
• Walphos
• Josiphos 

These ligand systems extend PMC’s established portfolio of precious metal precursors and preformed catalysts, enabling more integrated and flexible catalyst solutions.

Designed for performance and flexibility

The ligand families introduced are based on ferrocenyl backbone structures, which are widely recognized for their:

• High catalytic activity and robustness
• Strong coordination with various metal centers
• Excellent enantioselectivity
• Tunable electro steric properties

These characteristics make them highly versatile tools for demanding catalytic applications.

Proven across key applications

The expanded portfolio supports a wide range of reactions, including:

• Asymmetric hydrogenation
• Transfer hydrogenation
• Stereoselective cross-coupling
• Reductive amination

These applications highlight the versatility and reliability of the ligand systems in both research and industrial environments.

From research to industrial scale

With this integration, Umicore PMC enhances its ability to support customers along the entire development chain:

• Ligand selection and optimization
• Catalyst and process development
• Scale-up to industrial production
• Reliable global supply 

This end-to-end capability allows for a more consistent transition from early discovery to large-scale manufacturing.

Continuity for existing customers

For customers previously working with Solvias, this transition ensures continuity: 

• Core capabilities and expertise remain available
• Expanded infrastructure and portfolio through PMC
• Ongoing support to continue projects without disruption 

This approach is designed to provide stability while opening up additional possibilities through a broader technology base.

Looking ahead

The integration of ligand and screening capabilities is a key milestone in PMC’s ongoing development. By combining expertise, technologies, and infrastructure, Umicore PMC continues to evolve its offering for customers in catalysis and beyond.

 Let’s create good chemistry. Together.