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Chiralyst® Ru843

Chiralyst® Ru843

Chemical properties

Chemical formula

C48H38O4P2Ru

Empirical formula

Ru[(S)-BINAP](OAc)2

Molecular weight

841.84

Metal

Ru

Theoretical metal content

12

Physical state

powder

Color

orange

Metal purity

99.9

Applications & references

Description

Catalytic asymmetric hydrogenation of functionalized acrylic acid derivatives for the synthesis of pharmaceutically active substances.

Reference: US2005 0070714

 

Asymmetric hydrogenation of diketenes.

Reference: J. Org. Chem. 1995, 60, 357 (DOI: 10.1021/jo00107a014)

 

Asymmetric hydrogenation of five-membred α,β-unsaturated carbonyl compounds.

Reference: J. Org. Chem. 1995, 60, 357 (DOI: 10.1021/jo00107a014)

 

Hydroxyl directed hydrogenation in the total synthesis of zaragozic acids.

Reference: Chem. Eur. J. 2011, 17, 3335 (DOI: 10.1002/chem.201003399)

 

Asymmetric hydrogenation toward the general asymmetric synthesis of isoquinoline alkaloids, e.g. morphine.

Reference: Tetrah. 2006, 62, 5448 (DOI: 10.1016/j.tet.2006.03.055)