Chiralyst® Ru762

Applications & references

Description

Preparation of (3S,4S)-1-benzyl-4-chlorophenyl-pyrolidine-3-carboxylic acids via asymmetric hydrogenation; these compounds are important starting materials or intermediates in the synthesis of pharmaceutically active compounds, e.g. for the treatment of central nervous system disorders.

Reference: US2010 0152462

Synthesis of cis-substituted cyclic ß-aryl or- heteroaryl carboxylic acids in high diastereo- and enantioselectivity by asymmetric hydrogenation.

Reference: US2007 0232653