Chiralyst® Ru842

Diacetato[(R)-2,2'-bis(diphenylphosphino)-1,1'-binaphthyl]ruthenium(II)

CAS Number: 325146-81-4

Applications & references

Description

Asymmetric hydrogenation of ß-ketoester for the enantioselective synthesis of (R)-d-lactones.

Reference: WO2001 057014

Enantioselective synthesis of levetiracetam including asymmetric hydrogenation of (Z)-2-(2-oxopyrrolidin-1-yl)but-2-enamide.  

Reference: WO2001 064637

Synthesis of (S)-fluoromethyldihydro-furan-2-one for the manufacture of pyrido[2,1-a]isoquinoline derivatives which are useful for treatment or prophylaxis of diseases.

Reference: WO2006 125728

Asymmetric hydrogenation of five-membred α,β-unsaturated carbonyl compounds.

Reference: J. Org. Chem. 1995, 60, 357 (DOI: 10.1021/jo00107a014)