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Chiralyst® Ru1251

Chiralyst® Ru1251

Chemical properties

Chemical formula

C74H102O6P2Ru

Empirical formula

Ru[(R)-3,5-tBu-MeO-BIPHEP](OAc)2

Molecular weight

1250.64

Metal

Ru

Theoretical metal content

8

Physical state

powder

Color

yellow green

Metal purity

99.9

Applications & references

Description

Asymmetric hydrogenation of (Z)-methyl 3-amino-4-methoxy butenoate.

Reference: Org. Proc. Res. Dev. 2011, 15, 353 (DOI: 10.1021/op1002775)

 

Synthesis of (S)-fluoromethyldihydro-furan-2-one for the manufacture of pyrido[2,1-α]isoquinoline derivatives which are useful for treatment or prophylaxis of diseases.

Reference: WO2006 125728

 

Asymmetric hydrogenation of pyrone derivatives.

Reference: J. Org. Chem. 1999, 64, 5768 (DOI: 10.1021/jo982215l)

 

Asymmetric hydrogenation of methylcyclopentanone derivatives.

Reference: J. Org. Chem. 1999, 64, 5768  (DOI: 10.1021/jo982215l)