Chiralyst Ru762

Chiralyst Ru762

Chemical properties

Chemical formula

C34H30O10P2Ru

Empirical formula

Ru[(R)-2-Furyl-MeO-BIPHEP](OAc)2

Molecular weight

761.62

Metal

Ru

Theoretical metal content

13

Physical state

powder

Color

light yellow, brown

Metal purity

99.95

Applications & references

Preparation of (3S,4S)-1-benzyl-4-chlorophenyl-pyrolidine-3-carboxylic acids via asymmetric hydrogenation; these compounds are important starting materials or intermediates in the synthesis of pharmaceutically active compounds, e.g. for the treatment of central nervous system disorders.

Reference: US2010 0152462

 

Synthesis of cis-substituted cyclic ß-aryl or- heteroaryl carboxylic acids in high diastereo- and enantioselectivity by asymmetric hydrogenation.

Reference: US2007 0232653