Chiralyst Ru762

Diacetato[(R)-2,2‘-Bis(di-2-furanylphosphino)-6,6‘-dimethoxy-1,1‘-biphenyl]ruthenium(II)

CAS Number: 952040-51-6

Product class: M-P, Homogeneous Catalysts, M-O, Acetate Ligands, Phosphorus Ligands - Chiral

Reaction type: Hydrogenation, Asymmetric Reactions, Asymmetric Hydrogenation, Transfer Hydrogenation

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Applications & references

Preparation of (3S,4S)-1-benzyl-4-chlorophenyl-pyrolidine-3-carboxylic acids via asymmetric hydrogenation; these compounds are important starting materials or intermediates in the synthesis of pharmaceutically active compounds, e.g. for the treatment of central nervous system disorders.

Reference: US2010 0152462

Synthesis of cis-substituted cyclic ß-aryl or- heteroaryl carboxylic acids in high diastereo- and enantioselectivity by asymmetric hydrogenation.

Reference: US2007 0232653