Chiralyst Rh640

[((S,S)-2-Amino-1,2-diphenylethyl)[(4-tolyl)sulfonyl]amido](chloro)pentamethylcyclopentadienylrhodium(I)

CAS Number: 219944-99-7

Product class:

Reaction type:

Chemical properties

Chemical formula

C₃₁H₃₆N₂ClO₂SRh

Empirical formula

Rh[(S,S)-TsDPEN](C₅Me₅)Cl

Molecular weight

639.06

Metal

Theoretical metal content

Physical state

crystalline

Color

orange brown

Metal purity

99.95

Applications & references

Asymmetric reduction of α-sulfonyloxy acetophenone compound yielding an optically active 2-sulfonyloxy-1-phenylethanol derivative with high enantiomer excess.

Reference: WO2008 054155

Transfer hydrogenation of aromatic ß-ketoester for the synthesis of secondary aminoalcohols.

Reference: WO2005 028437

Asymmetric transfer hydrogenation of N-sulfonyl ketimine derivatives.

Reference: Tetrah. Asym. 2010, 21, 800 (DOI: 10.1016/j.tetasy.2010.04.047)

Asymmetric transfer hydrogenation of 2-tosyloxy-1-(4-hydroxyphenyl)ethanones derivatives leading to an efficient synthetic route of ß-adrenergic agonists.

Reference: Tetrah. Asym. 2007, 18, 2662 (DOI: 10.1016/j.tetasy.2007.10.046)

Request a quote or MSDS

Get in touch

Your contact person

Horiguchi Yoshiaki

T: +81 (3) 6685 3069

Xiaofang Bi

T: +86 (21) 2411 6870

Chinmay Pandya

T: +91 (22) 6627 5656

Heidi Heuser

T: +49 (6181) 59 2413

Phil Chalabi

T: +1 (918) 266 4826

Heidi Heuser

T: +49 (6181) 59 2413

Chiralyst Rh640

Chiralyst Rh640

[((S,S)-2-Amino-1,2-diphenylethyl)[(4-tolyl)sulfonyl]amido](chloro)pentamethylcyclopentadienylrhodium(I)

Chemical properties

Applications & references

Asymmetric reduction of α-sulfonyloxy acetophenone compound yielding an optically active 2-sulfonyloxy-1-phenylethanol derivative with high enantiomer excess.

Transfer hydrogenation of aromatic ß-ketoester for the synthesis of secondary aminoalcohols.

Asymmetric transfer hydrogenation of N-sulfonyl ketimine derivatives.

Asymmetric transfer hydrogenation of 2-tosyloxy-1-(4-hydroxyphenyl)ethanones derivatives leading to an efficient synthetic route of ß-adrenergic agonists.

Request a quote or MSDS

Your contact person

Horiguchi Yoshiaki

Xiaofang Bi

Chinmay Pandya

Heidi Heuser

Phil Chalabi

Heidi Heuser

Related products

Chiralyst Rh1228

Chiralyst Rh840

Chiralyst P1182

Chiralyst P374

Chiralyst P461

Chiralyst P407

Chiralyst P493

Chiralyst P310

Chiralyst Rh1119

Chiralyst Rh660

Chiralyst P468