Chiralyst® Rh639
Chiralyst® Rh639
Applications & references
Description
Asymmetric reduction of α-sulfonyloxy acetophenone compound yielding an optically active 2-sulfonyloxy-1-phenylethanol derivative with high enantiomer excess.
Reference: WO2008 054155
Asymmetric synthesis of ß-amino alcohols by rhodium catalyzed transfer hydrogenation of α-keto imines.
Reference: Tetrah. Asym. 2010, 21, 2244 (DOI: 10.1016/j.tetasy.2010.07.004)
One pot synthesis of sterically active epoxides starting from α-chloroacetophenones including a asymmetric transfer hydrogenation step.
Reference: Tetrah. 2004, 60, 7411 (DOI: 10.1016/j.tet.2004.06.076)
Synthesis of optically active styrene oxides by asymmetric reduction of 2-chloroacetophenones.
Reference: Org. Lett. 2002, 4, 4373 (DOI: 10.1021/ol020213o)
Enantioselective preparation of cyclic sulfamidates by using asymmetric transfer hydrogenation.
Reference: Org. Lett. 2010, 12, 4184 (DOI: 10.1021/ol1017905)
Asymmetric transfer hydrogenation of α-aminoalkyl α’-chloromethylketones yielding useful intermediates for the total synthesis of inhibitors of HIV protease and ß-secretase in Alzheimer disease.
Reference: J. Org. Chem. 2004, 69, 7391 (DOI: 10.1021/jo0491455)