Chiralyst® Ru636
Chiralyst® Ru636
[((R,R)-2-Amino-1,2-diphenylethyl)[(4-tolyl)sulfonyl]amido](chloro)(p-cymene)ruthenium(II)
CAS Number: 192139-92-7
Applications & references
Description
Synthesis of optically active 4-hydroxy-2,6,6-trimethyl-cyclohex-3-enone derivatives via enantioselective transfer hydrogenation of the corresponding enolethers for the production of (3S,3’S)-astaxantin.
Reference: WO2008 116714
Asymmetric transfer hydrogenation of functionalized ketones for the drug substance synthesis, e.g. rivastigimine for the treatment of Alzheimer’s disease.
Reference: WO2010 0072798
Preparation of optically active aromatic epoxides by asymmetric transfer hydrogenation of α-chlorinated ketones.
Reference: Tetrah. 2004, 60, 7411 (DOI: 10.1016/j.tet.2004.06.076)
Asymmetric transfer hydrogenation of benzyl with formic acid.
Reference: Org. Lett. 1999, 1, 1119 (DOI: 10.1021/ol990226a)
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