Chiralyst Ru637

Chiralyst Ru637

[((S,S)-2-Amino-1,2-diphenylethyl)[(4-tolyl)sulfonyl]amido](chloro)(p-cymene)ruthenium(II)

CAS Number: 192139-90-5

Product class: M-C, Homogeneous Catalysts, M-N, Chiral Ligands, Arene/Aryl Ligands

Reaction type: Hydrogenation, Asymmetric Reactions, Asymmetric Hydrogenation, Transfer Hydrogenation

Chemical properties

Chemical formula

C31H35N2ClO2SRu

Empirical formula

Ru[(S,S)-TsDPEN](p-cymene)Cl

Molecular weight

636.22

Metal

Ru

Theoretical metal content

16

Physical state

powder

Color

orange

Metal purity

99.95

Applications & references

Synthesis of optically active 4-hydroxy-2,6,6-trimethyl-cyclohex-3-enone derivatives via enantioselective transfer hydrogenation of the corresponding enolethers for the production of (3S,3’S)-astaxantin.

Reference: WO2008 116714

Asymmetric transfer hydrogenation of imines to amines using isopropanol and formic acid as hydrogen source. 

Reference: WO2010 022518

Asymmetric transfer hydrogenation of benzil with formic acid and triethylamine.

Reference: Org. Lett. 1999, 1, 1119 (DOI: 10.1021/ol990226a); Org. Synth. 2005, 82, 10 (DOI: 10.15227/orgsyn.082.0010)

Reduction of aliphatic 1,3-diketones.

Reference: Org. Lett. 2002, 4, 1263 (DOI: 10.1021/ol025527q)

Asymmetric transfer hydrogenation of an alkynone derivative with isopropanol as hydrogen source in the total synthesis of zaragozic acids.

Reference: Chem. Eur. J. 2011, 17, 3335 (DOI: 10.1002/chem.201003399)

Asymmetric transfer hydrogenation of functionalized cyclic ketones.

    

Reference: Org. Synth. 2005, 82, 10 (DOI: 10.15227/orgsyn.082.0010 )