Umicore Grubbs Catalyst M101

Dichloro(3-phenyl-1H-inden-1-ylidene)bis(tricyclohexylphosphine)ruthenium(II)

CAS Number: 250220-36-1

Product class:

Reaction type:

Chemical properties

Chemical formula

C₅₁H₇₆Cl₂P₂Ru

Empirical formula

Ru(PCy₃)₂(Ind)Cl₂

Molecular weight

923.08

Metal

Theoretical metal content

Physical state

powder

Color

brown

Metal purity

99.95

Legal information

WO 2010 037550 and WO 2014 001291 apply.

Applications & references

Total synthesis of macrocyclic HCV protease inhibitor with RCM as key step.

Reference: US2009 0163706

Metathesis key step in the synthesis of cyclic tripyrole pigment nonylprodigiosin.

Reference: J. Org. Chem. 1999, 64, 8275 (DOI: 10.1021/jo991021i)

Total synthesis of macrocyclic compounds which are useful as inhibitors of hepatitis C virus N33 protease.

Reference: US2007 0027071

Macrocyclization step by ring closing metathesis in the synthesis of turrianes.

Reference: Chem. Eur. J. 2002, 8, 1856 (10.1002/1521-3765(20020415)8:8<1856::AID-CHEM1856>3.0.CO;2-RView)

Ring closing metathesis.

Reference: Chem. Comm. 2008, 2726 (DOI: 10.1039/B718287B)

Enyne cycloisomerization.

Reference: Chem. Comm. 2008, 2726 (DOI: 10.1039/B718287B)

Nucleophilic addition of acids to alkynes.

Reference: Chem. Comm. 2008, 2726 (DOI: 10.1039/B718287B)

Diastereoselective double ring closing metathesis.

Reference: Chem. Comm. 2008, 2726 (DOI: 10.1039/B718287B)

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Get in touch

Your contact person

Chinmay Pandya

T: +91 (22) 6627 5656

Xiaofang Bi

T: +86 (21) 2411 6870

Heidi Heuser

T: +49 (6181) 59 2413

Horiguchi Yoshiaki

T: +81 (3) 6685 3069

Phil Chalabi

T: +1 (918) 266 4826

Heidi Heuser

T: +49 (6181) 59 2413

Please order your research quantities at Merck / MilliporeSigma

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Umicore Grubbs Catalyst M101

Umicore Grubbs Catalyst M101

Dichloro(3-phenyl-1H-inden-1-ylidene)bis(tricyclohexylphosphine)ruthenium(II)

Chemical properties

Legal information

Applications & references

Total synthesis of macrocyclic HCV protease inhibitor with RCM as key step.

Metathesis key step in the synthesis of cyclic tripyrole pigment nonylprodigiosin.

Total synthesis of macrocyclic compounds which are useful as inhibitors of hepatitis C virus N33 protease.

Macrocyclization step by ring closing metathesis in the synthesis of turrianes.

Ring closing metathesis.

Enyne cycloisomerization.

Nucleophilic addition of acids to alkynes.

Diastereoselective double ring closing metathesis.

Request a quote or MSDS

Your contact person

Chinmay Pandya

Xiaofang Bi

Heidi Heuser

Horiguchi Yoshiaki

Phil Chalabi

Heidi Heuser

Please order your research quantities at Merck / MilliporeSigma

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