Chemical properties

Chemical formula


Empirical formula


Molecular weight [g/mol]




Theoretical metal content [%]


Physical state




Metal purity [%]


Applications & References

Suzuki coupling reaction as key synthesis step in the preparation of the chiral, nonracemic 3-aryl piperidine (OSU 6162), a potential central nervous system agent.

Reference: Org. Proc. Res. Dev. 2003, 7, 385. (DOI: 10.1021/op025620u)

Aryl-aryl Negishi coupling reaction in the preparation of 5-[2-Methoxy-5-(4-pyridinyl)phenyl]-2,1,3-benzoxadiazole (PDE472), a selective inhibitor of the phosphodiesterase PDE4D isoenzyme, which is well known as drug target for the treatment of asthma.

Reference: Org. Proc. Res. Dev. 2003, 7, 436. (DOI: 10.1021/op025615q)

Palladium catalyzed synthesis of trans-1,2-diazetidines by cyclization of 2,3-allenyl hydrazines with aryl halides.

Reference: Angew. Chem. Int. Ed. 2008, 47, 4581. (DOI: 10.1021/anie.200800364)

Palladium catalyzed cross coupling reaction of a-diazocarbonyl compounds with arylboronic acids providing access to a-aryl substituted a,b-unsaturated carbonyl compounds.

Reference: J. Am. Chem. Soc. 2008, 130, 1566. (DOI: 10.1021/ja0782293)

Palladium catalyzed intermolecular decarboxylative coupling in the presence of reactive C-H groups.

Reference: J. Org. Chem. 2010, 75, 1550. (DOI: 10.1021/jo9022793)

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